Co-founder of AO Legacy, Daughter of deceased Viet vet exposed to AO
A small pilot study led by a Department of Veterans Affairs (VA) researcher found that a nasal insulin spray improved memory, thinking skills, and functional ability in people with mild cognitive impairment and Alzheimer’s disease. Currently, there are no effective treatments to delay or prevent Alzheimer’s.
Previous studies found that low brain levels of insulin—the main hormone that turns sugar in the bloodstream into energy for cells—could contribute to Alzheimer’s. Based on these findings, VA’s Dr. Suzanne Craft has led efforts to test the benefits of restoring normal insulin function in the brain.
The new study tested a nasal spray that delivers insulin quickly and directly to the brain, with no harmful side effects, such as increased insulin levels throughout the whole body. The trial included 104 adults with either amnestic mild cognitive impairment—in which people have memory loss that may progress to Alzheimer’s—or mild to moderate Alzheimer’s disease.